PD-L1 28-8
Description- This is a FDA-approved test which helps in the prediction of response to nivolumab (OPDIVO) for patients with nonsquamous nonsmall cell lung cancer (NSCLC) or melanoma
Methodology: Immunohistochemistry
TAT: 3-5 days
Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- - i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
iii) Paraffin block with no tumor tissue remaining.
iv) Specimens fixed in any fixative other than 10 percent neutral buffered formalin Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable
