DUSP22-IRF4

DESCRIPTION – gene rearrangements involving the DUSP22- IRF4 gene region have been reported in CD30 positive and ALK negative anaplastic large cell lymphoma and are associated with favorable clinical outcome. Rearrangement has been reported in a subset of patients with lymphomatoid papulosis. Testing may identify large B-cell lymphoma with IRF4 gene rearrangement

METHODOLOGY – fluorescence in situ hybridization (FISH)

TURN AROUND TIME – 15 days

PATEINT PREPARATION –

COLLECT – tumor tissue

SPECIMEN PREPARATION – formalin fixed paraffin embedded tissue block. Protect the slides from excessive heat

STORAGE/TRANSPORT TEMPERATURE – room temperature

STABILITY – ambient: indefinitely; refrigerated: indefinitely

UNACCEPTABLE CONDITIONS – clotted specimens

MRP – 46500.00

SPECIAL INSTRUCTIONS – clinical history is mandatory