Alpha-1- antitrypsin

Description- Alpha-1-AT; expressed by cells of histolytic origin; Aids in identifying germ-cell and histolytic neoplasms, as well as embryonal and some lung carcinomas; This test determines specific AAT protein variants in an individual with reduced concentration of AAT (<90mg/dL).

Approach - Qualitative Isoelectric Focusing/Immunoturbidimetry

Specimen Required - Patient Preparation

Collect - Serum Separator Tube (SST) or Plain Red.

Specimen Preparation- Transfer 1 mL serum to Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature- Refrigerated sample.

Specimen rejection - Grossly hemolyzed specimens are rejected.

Stability - After separation from cells: Ambient: 1 week; Refrigerated: 3 months; frozen: 3 months (avoid repeated freeze/thaw cycles)